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目的分析急性脑卒中并发上消化道出血的相关危险因素。方法选取在我院进行治疗的脑卒中患者90例,按是否合并上消化道出血分为对照组(未并发上消化道出血,58例)和观察组(并发上消化道出血,32例)。分析两组患者饮酒、消化道病史、疾病程度、病变部位等临床资料。结果与对照组比较,观察组重度急性脑卒中、丘脑出血、大面积脑梗死、出血性脑卒中、肺炎、消化道病史、饮酒史发生率明显提高,差异有统计学意义(P<0.05);观察组吸烟、脑卒中史与对照组比较,差异无统计学意义(P>0.05);观察组肺炎及多器官功能障碍综合征(MODS)发生率较对照组明显降低,差异有统计学意义(P<0.05)。结论病情程度、病变部位、脑卒中类型、消化道病史、饮酒、肺炎是造成急性脑卒中患者发生上消化道出血的危险因素。
Objective To analyze the risk factors associated with upper gastrointestinal bleeding in acute stroke. Methods Ninety patients with stroke who were treated in our hospital were divided into control group (without upper gastrointestinal bleeding, 58 cases) and observation group (with upper gastrointestinal bleeding, 32 cases) according to whether they had upper gastrointestinal bleeding. Analysis of two groups of patients drinking, gastrointestinal history, degree of disease, lesion and other clinical data. Results Compared with the control group, the incidence of severe acute stroke, thalamic hemorrhage, large cerebral infarction, hemorrhagic stroke, pneumonia, gastrointestinal history and alcohol drinking history in the observation group was significantly increased (P <0.05). There were no significant differences in the smoking and stroke history between the observation group and the control group (P> 0.05). The incidence of pneumonia and multiple organ dysfunction syndrome (MODS) in the observation group was significantly lower than that in the control group (P <0.05) P <0.05). Conclusion The severity of the disease, the location of the lesion, the type of stroke, the history of gastrointestinal tract, alcohol consumption and pneumonia are the risk factors of upper gastrointestinal bleeding in acute stroke patients.