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目的探讨重度子痫前期及子痫终止妊娠时机和方式对孕妇及围生儿预后的影响。方法回顾性分析2006年1月至2008年12月在我院住院分娩的重度子痫前期产妇45例,子痫产妇5例,按终止妊娠的孕周将其分三组:<34周组、34～36+6周组、≥37周组。按终止妊娠的方式将其分为两组:剖宫产组和阴道产组。对比分析终止妊娠时机和方式与新生儿窒息及病死率的关系。结果孕周<34周组与34～36+6周组、≥37周组三组的新生儿窒息及病死率比较差异有统计学意义(P<0.05),34～36+6周的新生儿窒息及病死率最低。剖宫产组的新生儿窒息及病死率明显低于阴道产组(P<0.05)。结论适时终止妊娠是治疗重度子痫前期和子痫有效的方法,34～36+6周为终止妊娠的最佳时机;终止妊娠的最佳方式为剖宫产。
Objective To investigate the effect of timing and mode of termination of pregnancy and severe preeclampsia on the prognosis of pregnant women and perinatal infants. Methods Retrospective analysis of 45 cases of severe preeclampsia and 5 cases of eclampsia in hospital from January 2006 to December 2008 in our hospital were divided into three groups according to gestational weeks of termination of pregnancy: 34 ~ 36 + 6 weeks group, ≥ 37 weeks group. They were divided into two groups according to the method of termination of pregnancy: cesarean section group and vaginal delivery group. The relationship between the timing and mode of termination of pregnancy and neonatal asphyxia and mortality was compared and analyzed. Results There were significant differences in neonatal asphyxia and case fatality between the 34 weeks and 34-36 + 6 weeks gestation group and the 37 weeks gestation group (P <0.05). Neonates 34 to 36 + 6 weeks Suffocation and mortality are lowest. Neonatal asphyxia and mortality in the cesarean section group were significantly lower than those in the vaginal delivery group (P <0.05). Conclusion The timely termination of pregnancy is an effective method for the treatment of severe preeclampsia and eclampsia. 34-36 + 6 weeks is the best time to terminate the pregnancy. The best way to terminate the pregnancy is caesarean section.