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目的研究血必净对急性颅脑损伤患者血清C反应蛋白(CRP)的影响。方法选取2011年3月~2013年3月在本院接受治疗的重症脑挫裂伤患者50例,随机将其分为对照组和研究组各25例,两组患者均常规综合治疗及手术治疗,在对照组的基础上研究组加用血必净注射液治疗。结果经治疗两组格拉斯哥昏迷评分(GCS)较治疗前增高,至7 d时差异有统计学意义(P<0.05),且研究组明显高于对照组(P<0.05),研究组与同期的对照组的相比CRP降低更明显,差异具有统计学意义(P<0.05)。结论血必净注射液可显著降低急性颅脑损伤患者血清C反应蛋白水平,同时减轻脑水肿,有效的提高治疗效果,具有临床推广价值。
Objective To investigate the effect of Xuebijing on serum C-reactive protein (CRP) in patients with acute craniocerebral injury. Methods Fifty patients with severe contusion and laceration of brain treated in our hospital from March 2011 to March 2013 were randomly divided into control group and study group of 25 cases. Both groups were treated by conventional comprehensive treatment and surgical treatment , In the control group based on the study group plus Xuebijing injection treatment. Results The Glasgow Coma Scale (GCS) of the two groups after treatment was higher than that before treatment, and the difference was statistically significant (P <0.05) on the 7th day, and the study group was significantly higher than the control group (P <0.05) The CRP decrease in the control group was more significant, the difference was statistically significant (P <0.05). Conclusion Xuebijing injection can significantly reduce serum C-reactive protein levels in patients with acute brain injury, while reducing brain edema, effectively improve the treatment effect, with clinical value.