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1973～1990年,在黄陵县病区进行了缺硒与克山病关系的临床研究,结果表明:(1)口服亚硒酸钠使人体硒含量提高至非病区农村水平,即可有效地预防急性发病(包括急型和亚急型);硒盐是一种生活化的补硒方法,值得推广;(2)克山病发病与人体硒水平呈显著负相关,人体硒水平达到非病区水平后,慢型和潜在型仍有新发,其年发病率分别为1.9/万和32.4/万;(3)结合有关研究结果对低硒与克山病发病的可能关系进行了评估,认为低硒是克山病发病的一个基本水土因素,但不是唯一因素。
From 1973 to 1990, a clinical study on the relationship between Se deficiency and Keshan disease was carried out in Huangling County ward. The results showed that: (1) Oral administration of sodium selenite increased selenium content in rural areas to non-ward rural areas, (Including acute and subacute types); Selenium is a life-saving selenium supplement method that deserves promotion; (2) The incidence of Keshan disease is significantly negatively correlated with human selenium level, and the level of human selenium reaches non- The prevalence of chronic sequelae and latent sequelae were still higher than that of the control group, with annual incidence rates of 1.9 / million and 32.4 / million, respectively. (3) The possible relationship between low selenium and Keshan disease was evaluated based on the results , That low selenium is Keshan disease incidence of a basic water and soil factors, but not the only factor.