论文部分内容阅读
目的:探讨常频机械通气(CMV)与高频振荡通气(HFOV)在重症新生儿呼吸衰竭治疗中的应用价值。方法:选取2014年3月至2015年12月肇庆市高要区人民医院收治的60例新生儿重症呼吸衰竭患者作为研究对象,按照随机数字表法分为CMV组和HFOV组,每组各30例。对比两组呼吸机应用时间、上机后血气分析指标、转归情况及并发症发生率等指标。结果:CMV组通气总持续时间与撤机后总给氧时间均高于HFOV组(P<0.05)。上机后24 h,两组pH与SpO_2比较,差异无统计学意义(P>0.05);HFOV组PaCO_2较CMV组降低(P<0.05),PaO_2、FiO_2与OI则明显高于CMV组(P<0.05)。CMV组和HFOV组患儿生存率、并发症发生率分别为90.0%和93.3%、13.3%和16.7%,两组比较,差异无统计学意义(P>0.05)。结论:与CMV通气方式相比较而言,HFOV可明显改善新生儿重症呼吸衰竭的低氧状态,改善呼吸困难症状。
Objective: To investigate the value of frequent mechanical ventilation (CMV) and high frequency oscillatory ventilation (HFOV) in the treatment of severe neonatal respiratory failure. Methods: From March 2014 to December 2015, 60 cases of neonatal severe respiratory failure admitted to Gaoyao District People’s Hospital of Zhaoqing City were selected as the research object and divided into CMV group and HFOV group according to random number table example. Compare the two sets of ventilator application time, blood gas analysis indicators on the machine, the outcome of the situation and the incidence of complications and other indicators. Results: The total duration of ventilation and the total oxygenation time after weaning in CMV group were higher than those in HFOV group (P <0.05). Compared with CMV group, the PaCO_2 in HFOV group was lower than that in CMV group (P <0.05), PaO_2, FiO_2 and OI were significantly higher than those in CMV group (P> 0.05) <0.05). The survival rates and complication rates in children with CMV and HFOV were 90.0% and 93.3%, 13.3% and 16.7% respectively. There was no significant difference between the two groups (P> 0.05). CONCLUSION: Compared with CMV ventilation, HFOV can significantly improve the hypoxia status of neonatal severe respiratory failure and improve the symptoms of dyspnea.