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用银胶染色技术，对六亚甲基二乙酰胺（ｈｅｘａｍｅｔｈｙｌｅｎｅｂｉｓａｃｅｔａｍｉｄｅ，ＨＭＢＡ）诱导后的人粘液表皮样癌细胞系ＭＥＣ－１细胞进行核仁区嗜银蛋白染色，结果发现诱导组细胞内嗜银颗粒粗大，数目变少为４．９６±３．１１，对照组为９．１４±５．６６，两组有显著差异（Ｐ＜０．０１）。这可能与细胞分化有关。
Silver staining was performed on human mucoepidermoid carcinoma cell line MEC-1 cells induced by hexamethylene bisacetamide (HMBA). Silver staining was performed in the nucleolar region. The granules were coarse, the number was reduced to 4.96±3.11, and the control group was 9.14±5.66. There was a significant difference between the two groups (P<0.01). This may be related to cell differentiation.