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对５２例胃肠道恶性肿瘤病人进行根治手术前后血清ＳＩＬ－２Ｒ水平表达的动态研究，并与４２例健康人对照比较结果显示：（１）胃肠道恶性肿瘤病人术前血清ＳＩＬ－２Ｒ水平为（４７８８５±１４１８８）Ｕ／ｍＬ，健康人对照组为（２５６４３±５９２９）Ｕ／ｍＬ，胃肠道恶性肿瘤病人术前血清ＳＩＬ－２Ｒ水平明显高于健康对照组（Ｐ＜００１）；（２）根治术后１０ｄ测定患者血清ＳＩＬ－２Ｒ水平为（２３１８２±１３９８９）Ｕ／ｍＬ，与手术前相比较，明显降低（Ｐ＜００１）结论：胃肠道恶性肿瘤病人机体细胞免疫功能在荷瘤状态时低下，出现免疫抑制物ＳＩＬ－２Ｒ水平明显增高的异常现象；根治手术切除肿瘤及转移淋巴结后，ＳＩＬ－２Ｒ水平明显降低提示：动态检测ＳＩＬ－２Ｒ水平是胃肠道恶性肿瘤病人病情监测、疗效判断的一项参考指标
The dynamic study of serum SIL-2R levels in 52 patients with gastrointestinal cancer before and after radical surgery was compared with 42 healthy controls. Results showed that: (1) Preoperative serum SIL-2R in gastrointestinal cancer patients The level was (478 85 ± 141 88) U/mL, and the healthy control group was (256 43 59 29) U/mL. The serum SIL-2R levels in patients with gastrointestinal cancer were significantly higher than those in healthy subjects. The serum SIL-2R level was (23182±13989)U/mL in the control group (P<001); (2) The serum SIL-2R level was significantly lower than that before the operation (P<0). 01) Conclusion: The cellular immune function of patients with gastrointestinal cancer is low in the tumor-bearing state, and there is an abnormal increase in the level of immunorepressor SIL-2R; SIL-2R levels after radical resection of tumors and metastatic lymph nodes Significantly reduced hemorrhoids tips: dynamic detection of SIL-2R levels is gastrointestinal Patients with malignant disease surveillance, a reference index determine the efficacy of