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自身免疫性溶血性贫血(autoimmune hemolytic anemia,AIHA)是人类免疫功能紊乱产生抗自身红细胞的抗体,与红细胞表面的抗原相结合或激活补体使红细胞寿命缩短的一种获得性疾病,约占所有溶血疾病的1/3〔1〕。自身抗体可分为温抗、冷抗体、温冷混合3种类型,本文主要对温抗体进行讨论。由于温自身抗体的存在,常常难以找到相容的血液,同时它还能掩盖同种抗体的存在,所以
Autoimmune hemolytic anemia (AIHA) is an anti-human red blood cell antibody that is produced by human immune dysfunction. It is an acquired disease that shortens the life span of red blood cells by binding to the antigen on erythrocytes or activating complement, Disease 1/3 〔1〕. Autoantibodies can be divided into temperature resistance, cold antibodies, mixed cold and warm three types, this article mainly discusses the warm antibodies. Because of the presence of warm autoantibodies, it is often difficult to find compatible blood, while it also masks the presence of alloantibodies, so