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伴发大疱损害的系统性红斑狼疮(SLE)国内外均有报道,但大疱损害与SLE的关系各家看法不一.现将本院近年来4例伴发大疱损害的SLE报告如下。患者4例,3例女性,1例男性;年龄16～30岁;SLE临床诊断皆符合ARA(1982)标准,其中2例先确诊SLE后出现大疱,另2例先诊为疱病(天疱疮、类天疱疮)后确诊为SLE。例1.甄某某,女,30岁。1979年9月因面部四肢红斑、关节痛、发烧。血沉41mm/h、CH_5040u.C_327u、IgG240u、ANA1:320+(SM),ds DNA17.6%,Hb 9.6g,尿蛋白(++)而诊断为SLE,经强的松30mg/d等治疗病情好转而停药。1982年5月复发.发烧,关节痛.面部红斑肿胀及躯干红斑风团,并有多数大疱损害,大疱发生在红斑基础上或健皮上,尼氏征(一),皮损活检
Bullae lesions associated with systemic lupus erythematosus (SLE) both at home and abroad have been reported, but the relationship between bullae damage and SLE different views of each. Now in our hospital in 4 cases with bulla injury SLE report is as follows . There were 4 patients, 3 women and 1 males, aged from 16 to 30 years old. The clinical diagnosis of SLE was in line with ARA (1982) criteria. Among them, 2 patients developed large blisters after diagnosis of SLE and 2 patients were diagnosed as blister Pemphigus, pemphigoid) was diagnosed as SLE. Example 1. Zhen Moumou, female, 30 years old. 1979 September due to facial erythema, joint pain, fever. ESR 41mm / h, CH_5040u.C_327u, IgG240u, ANA1: 320+ (SM), ds DNA17.6%, Hb 9.6g, urine protein (++) and diagnosed as SLE, prednisone 30mg / d and other treatment of the disease Reversal stopped. Recurrence in May 1982. Fever, arthralgia, facial erythema and swelling of the trunk and erythema, and the majority of bullous lesions, bullous lesions occur on the basis of erythema or on the skin, Niger’s sign (a), skin lesions biopsy