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目的了解沛县各种疫苗预防接种异常反应的发生情况,评价疫苗的安全性。方法对该系统2012—2013年所收集的AEFI病例进行描述性分析。结果全县共报告AEFI 555例,其中一般反应543例(97.84%),异常反应12例(2.16%)。男性报告数多于女性。2岁以儿童的内报告数占79.10%。在所使用的23种疫苗中有17种出现不良反应,报告平均发生率为6.78/万,百白破(无细胞)、白破、麻疹疫苗的发生率最高,分别分25.99/万、20.60/万、21.76/万。在报告的预防接种不良反应中,发热221例,局部红肿312例,硬结195例。结论应继续完善、规范AEFI监测系统,保障预防接种安全。
Objective To understand the occurrence of various vaccination abnormalities in Peixian and evaluate the safety of the vaccine. Methods Descriptive analysis of AEFI cases collected in the system from 2012 to 2013 was performed. Results A total of 555 AEFI cases were reported in the county, of which 543 (97.84%) were general reactions and 12 (2.16%) were abnormal reactions. Men report more than women. Children aged 2 years reported 79.10%. Of the 23 vaccines used, 17 showed adverse reactions, with an average reported incidence of 6.78 / million. The incidence of diphtheriae (no cell), white broken, and measles vaccines was the highest at 25.99 / million and 20.60 / Million, 21.76 / million. Adverse reactions in the reported vaccination, 221 cases of fever, local inflamed 312 cases, 195 cases of induration. Conclusion should continue to improve, standardize AEFI monitoring system to ensure the safety of vaccination.