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目的分析评价海南省2010年麻疹减毒活疫苗(MV)强化免疫效果。方法综合分析麻疹强化免疫接种率、麻疹监测系统资料及AEFI监测系统资料。结果全省强化免疫共接种8月龄～6岁目标儿童772850人,报告接种率为96.93%,其中常住儿童报告接种率为97.05%,流动儿童报告接种率96.19%,两组人群强化免疫接种率差异有统计学意义(χ2=253.557,P<0.05),分年龄组报告接种率均>95%,系统评估接种率为97.7%,调查两市县接种率无统计学意义(χ2=0.812,P>0.05),2010年、2011年、2012年全省麻疹发病率分别为0.5/100万,0.47/100万、0.33/100万。结论海南省2010年开展MV强化免疫进一步提高了8月龄～6岁儿童MV的接种率,确保了适龄儿童MV抗体水平,并形成人群有效的免疫屏障,从而巩固了我省提前消除麻疹的现有成绩,但是要确保实现2012年消除麻疹的目标,必须在确保常规免疫高接种率的同时进一步提高mv及时接种率,同时开展流动人口查漏补种工作。
Objective To analyze and evaluate the effect of boosting immunity of live attenuated measles vaccine (MV) in Hainan Province in 2010. Methods A comprehensive analysis of measles immunization coverage, measles surveillance system information and AEFI monitoring system information. Results A total of 772850 children aged from 8 months to 6 years were vaccinated in the province. The reported vaccination rate was 96.93%, of which the reported rate of resident children was 97.05% and that of migrant children was 96.19%. The intensified immunization rate The difference was statistically significant (χ2 = 253.557, P <0.05). The coverage rate of reporting in each age group was> 95% and the rate of systematic evaluation was 97.7%. There was no significant difference in the coverage rate between two counties (χ2 = 0.812, P > 0.05). The incidence rates of measles in 2010, 2011 and 2012 in the whole province were 0.5 / 1 million, 0.47 / 1 million and 0.33 / 1 million respectively. Conclusion Hainan Province in 2010 to carry out MV enhanced immunity to further improve the MV of 8 months to 6 years old children vaccination rate to ensure that the school-age children’s MV antibody levels and the formation of effective population immune barrier, thus consolidating the province to eliminate measles in advance However, to ensure that the goal of measles elimination in 2012 is achieved, it is necessary to further increase the timely vaccination rate of mv while ensuring the routine high immunization rate, and at the same time, carry out the leak detection and replanting of floating population.