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激素补充治疗可以全面系统呵护更年期女性健康,有效地缓解和治疗女性更年期综合征,还可以预防女性骨质疏松、心血管疾病和老年性痴呆等。激素补充治疗发展的几个阶段100多年前,雌激素被人们发现,但口服雌激素不能吸收天然雌二醇,易被胃肠道和肝脏破坏。第一个正式用于雌激素补充治疗的药物,是在1942年发现的结合雌激素倍美力。但专家随后发现,应用结合雌激素的妇女发生子宫内膜癌的风险增加。自20世纪80年代后,
Hormone replacement therapy can comprehensively protect the health of menopausal women, effectively alleviate and treat menopausal syndrome, but also can prevent osteoporosis, cardiovascular disease and senile dementia. Several stages of the development of hormone replacement therapy 100 years ago, estrogen was found, but oral estrogen can not absorb natural estradiol, easily damaged by the gastrointestinal tract and liver. The first drug officially used in estrogen replacement therapy was beta-estradiol, which was found in 1942. However, experts later found that women who use estrogen-conjugated estrogen have an increased risk of developing endometrial cancer. Since the 1980s,