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血小板的生理功能是参与止血和凝血,随着医学的发展,近年研究表明,血小板在动脉血栓栓塞、冠心病、脑血管病及高血压病等疾病的发病机理中起着重要作用;在临床工作中采用血小板抑制剂治疗和予防血栓栓塞性疾病,正在广泛开展,各种血小板抑制药物不断问世。本文介绍这方面的基础知识及进展。血小板的结构及生理功能血小板在电子显微镜下为卵园形,少量呈梭形,直径2～3微米,在骨髓中由巨核细胞形成。其超微结构分为三个区域: (一)外周区:由外衣、单位膜和膜下区组成。外衣为血小板最表面一层,与血小
The physiological function of platelets is involved in hemostasis and coagulation. With the development of medicine, recent studies have shown that platelets play an important role in the pathogenesis of arterial thromboembolism, coronary heart disease, cerebrovascular disease and hypertension. In clinical work The use of platelet inhibitors in the treatment and prevention of thromboembolic diseases, is being widely implemented, a variety of platelet inhibitory drugs continue to come out. This article describes the basics and progress in this area. Platelet structure and physiological function Platelets in the electron microscope for the egg-shaped garden, a small amount of fusiform, diameter of 2 to 3 microns in the bone marrow by the formation of megakaryocytes. The ultrastructure is divided into three areas: (A) the outer zone: the coat, the unit membrane and sub-membrane zone. Outer clothing is the most superficial layer of platelets, and blood