【摘 要】
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Two new tetralone derivatives named xylariol A (1) and B (2) were isolated from the EtOAc extract of the culture broth of Xylaria hypoxylon AT-028 (Xylariaceae)
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
Two new tetralone derivatives named xylariol A (1) and B (2) were isolated from the EtOAc extract of the culture broth of Xylaria hypoxylon AT-028 (Xylariaceae),and their structures were elucidated by MS,IR,1D-and 2D-NMR spectra,and by X-ray diffraction analysis.1 and 2 showed moderate cytotoxic activities against Hep G2 cells in the in vitro cytotoxic assay with IC_(50) values of 22.3 and 21.2μg/mL,respectively.
Two new tetralone derivatives named Xylariol A (1) and B (2) were isolated from the EtOAc extract of the culture broth of Xylaria hypoxylon AT-028 (Xylariaceae), and their structures were elucidated by MS, IR, ID- and 2D- NMR spectra, and by X-ray diffraction analysis.1 and 2 showed moderate cytotoxic activities against Hep G2 cells in the in vitro cytotoxic assay with IC 50 values of 22.3 and 21.2 μg / mL, respectively.
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