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目的:探讨早期液体复苏容量对脓毒性休克的治疗意义。方法:定义正平衡即液体入量大于液体出量,负平衡即液体入量小于液体出量。回顾性分析80例脓毒性休克患者入院后24h和入院后72h液体复苏正平衡组及负平衡组的资料,分析两组间患者的预后。结果:入院后24h内负平衡组,负平衡液体量-218±21.4ml,死亡率显著低于正平衡组,正平衡液体量3206±57.9ml(P<0.01)。入院后72h内负平衡组,负平衡液体量-278±25.9ml,死亡率显著低于正平衡组,正平衡液体量5265±98.7ml(P<0.01)。结论:脓毒性休克患者早期液体复苏容量负平衡可以降低病死率。
Objective: To investigate the therapeutic effect of early liquid resuscitation on septic shock. Method: Define a positive balance that is, the amount of liquid is greater than the amount of liquid output, the negative balance is the amount of liquid is less than the amount of liquid output. A retrospective analysis of 80 patients with septic shock after admission and 72 h after admission liquid resuscitation positive balance group and negative balance group data to analyze the prognosis of patients between the two groups. Results: In the negative balance group after 24 h admission, the volume of negative balance liquid was -218 ± 21.4 ml, the mortality rate was significantly lower than the positive balance group, and the positive balance liquid volume was 3206 ± 57.9 ml (P <0.01). Within 72 hours after admission, the negative balance group had a negative balance of -278 ± 25.9 ml, and the mortality rate was significantly lower than that of the positive balance group with a positive balance of 5265 ± 98.7 ml (P <0.01). Conclusions: Negative balance of early fluid resuscitation in patients with septic shock may reduce mortality.