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目的:探讨液基细胞学检查联合电子阴道镜下组织病理学检查在宫颈病变中的诊断价值。方法:回顾性分析我院妇科门诊924例临床可疑宫颈病变患者,行电子阴道镜活组织检查,其中301例妇女行液基细胞学检查联合电子阴道镜活组织检查(实验组),623例直接行阴道镜活组织检查(对照组),以组织学诊断为金标准,比较2组组织学诊断阳性检出率。结果:实验组组织学诊断阳性检出率为45.2%(136/301),其中宫颈上皮内瘤变占40.5%(122/301),浸润癌占4.7%(14/301);对照组组织学诊断阳性检出率为30.2%(188/623),其中宫颈上皮内瘤变占20.4%(127/623),浸润癌占9.8%(61/623)。2组诊断阳性检出率比较差异有统计学意义(P<0.01)。结论:液基细胞学联合电子阴道镜检查与单一阴道镜检查相比,提高了宫颈病变的诊断准确性。
Objective: To investigate the diagnostic value of liquid-based cytology combined with electronic colposcopy histopathological examination in cervical lesions. Methods: A retrospective analysis of 924 cases of clinically suspected cervical lesions in gynecology clinic of our hospital was performed by electronic colposcopy biopsy. Of the 301 women, liquid-based cytology combined with electronic colposcopy biopsy (experimental group), 623 direct Colposcopy biopsy (control group), with histological diagnosis as the gold standard, the positive rate of 2 sets of histological diagnosis was compared. Results: The positive rate of histological diagnosis was 45.2% (136/301) in the experimental group, of which 40.5% (122/301) of cervical intraepithelial neoplasia and 4.7% (14/301) of invasive carcinoma. The histological The positive rate of diagnosis was 30.2% (188/623), of which, cervical intraepithelial neoplasia accounted for 20.4% (127/623) and invasive carcinoma accounted for 9.8% (61/623). The positive rate of the two groups was statistically significant (P <0.01). Conclusion: Liquid-based cytology combined with electronic colposcopy improves the diagnostic accuracy of cervical lesions compared with single colposcopy.