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目的探究胰腺实性假乳头状肿瘤(SPTP)的临床病理学特征。方法对12例SPTP患者的临床资料进行回顾性分析。结果 12例SPTP患者中,女11例,男1例;患者平均年龄31.7岁。术后随访均无复发。肿瘤平均直径约7.6 cm,组织学示瘤细胞大小一致,片块区与乳头状结构相混,细胞核圆,核分裂不常见。免疫组化观察a-AT阳性(11/12),Vim阳性(12/12),CD10阳性(11/12),PR阳性(10/12),Syn阳性(4/12),EMA阴性(0/10)。结论胰腺实性假乳头状肿瘤是一种罕见的肿瘤,恶性程度低,多发于中年女性,治疗效果较好。
Objective To investigate the clinicopathological features of solid pseudopapillary tumor of pancreas (SPTP). Methods The clinical data of 12 patients with SPTP were analyzed retrospectively. Results Among 12 patients with SPTP, 11 were female and 1 was male; mean age was 31.7 years. No recurrence after follow-up. The average tumor diameter of about 7.6 cm, histological tumor cells showed the same size, piece area and papillary structure mixed, nuclear round, not common nuclear fission. The positive expression of a-AT (11/12), Vim positive (12/12), CD10 positive (11/12), PR positive (10/12), Syn positive / 10). Conclusions The solid pseudopapillary tumor of pancreas is a rare tumor with a low degree of malignancy and is often seen in middle-aged women. The treatment effect is good.