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目的观察联合应用不同根管充填糊剂治疗慢性根尖周炎的临床疗效。方法选取2007—2009年山东大学口腔医学院综合科门诊诊治的慢性根尖周炎患者298例(422颗牙),按患者就诊先后顺序随机分为4组。A组(AH Plus糊剂+Vitapex糊剂+牙胶尖)75例患者108颗牙,B组(AH Plus糊剂+牙胶尖)75例患者105颗牙,C组(Vitapex糊剂+牙胶尖)74例患者105颗牙,D组[氧化锌丁香油糊剂(ZOE)糊剂+牙胶尖]74例患者104颗牙。对4组术后7d、6个月、1年的临床疗效进行比较、分析。结果 298例患者根管充填7d后复查,A、C组术后反应轻,与B组比较,差异具有统计学差异(P<0.05);D组术后反应最重,与其他3组比较,差异均有统计学意义(均P<0.05)。根管充填6个月、1年后复查的结果没有差异(P>0.05),A组有效率最高,与其他3组比较,差异有统计学意义(P<0.05);D组有效率最低,与其他3组比较,差异有统计学意义(P<0.05)。结论 AH Plus糊剂+Vitapex糊剂+牙胶尖治疗慢性根尖周炎,既诱导了根尖周阴影区的骨质增生修复,又能使根尖孔形成完善的封闭,达到治愈根尖周炎、防止继发感染或复发的目的。
Objective To observe the clinical effect of combined application of different root canal filling paste in the treatment of chronic apical periodontitis. Methods A total of 298 cases (422 teeth) of chronic periapical periodontitis diagnosed and treated in the Department of Stomatology, Shandong University, 2007-2009 were randomly divided into 4 groups according to the order of their visits. A group (AH Plus + Vitapex paste plus gutta percha) 108 teeth in 75 patients, Group B (AH plus paste + gutta percha) 75 teeth in 105 patients, Group C (Vitapex paste + teeth Glue tip) 74 teeth, 105 teeth, Group D [ZOE paste + gutta percha] 74 teeth in 104 patients. The clinical efficacy of 4 groups after 7 days, 6 months and 1 year were compared and analyzed. Results 298 patients underwent root canal filling 7d after reexamination, A, C group postoperative response was light, compared with the B group, the difference was statistically significant (P <0.05); D group postoperative response was the heaviest, compared with the other three groups, The differences were statistically significant (all P <0.05). There was no difference between the two groups (P> 0.05). The effective rate was the highest in group A, and the difference was statistically significant (P <0.05) compared with the other three groups. The effective rate was the lowest in group D, Compared with the other three groups, the difference was statistically significant (P <0.05). Conclusion AH Plus + Vitapex paste + gutta percha crevicular treatment of chronic periapical periodontitis, not only induced periosteal hyperplasia repair periapical shadow area, but also to make the apical foramen perfect closed to achieve the apical period Inflammation, prevent secondary infection or recurrence purposes.