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本文对消化性溃疡引起严重胃肠道出血病例,比较了生长抑素(Somatostain)与甲氰咪胍的治疗功效。病例和方法:研究对象均为消化性溃疡引起的严重持久性急性出血(24小时需输血3单位以上)、慢性渗血(24小时均需输血2单位以上)或反复出血的住院病例。应用冰水洗胃、抗酸剂和输血等保守治疗至少4小时而出血未自发停止,以及因年龄、伴有疾病或健康不良等因素不适于紧急手术者,按顺序随机选择病例。治疗方案分为两组:(1)生长抑素组:一次静注250μg后,每小时输滴250μg,计48～120小时;(2)甲氰咪胍组:每4小时静注200mg,计48～120小时。全部病例放置
This article presents the case of severe gastrointestinal bleeding caused by peptic ulcer and compares the therapeutic efficacy of somatostain and cimetidine. Cases and Methods: All patients were hospitalized with severe and persistent acute bleeding caused by peptic ulcer (more than 3 units transfused in 24 hours), chronic bleeding (more than 2 units transfused in 24 hours) or recurrent bleeding. Patients should be randomized in order by applying ice-water gastric lavage, conservative treatment with antacids and blood transfusions for at least 4 hours without spontaneous bleeding, and those unsuitable for emergency surgery due to age, concomitant diseases or poor health. Treatment regimens were divided into two groups: (1) somatostatin group: a 250μg intravenous infusion, dropping 250μg per hour, accounting for 48 to 120 hours; (2) cimetidine group: every 4 hours intravenous injection of 200mg, total 48 ~ 120 hours. All cases were placed