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目的:分析左甲状腺素片治疗亚临床甲减患者的临床疗效及对血脂、心室功能的影响。方法:将化州市人民医院内分泌科2015年4月至2016年3月经临床确诊为亚临床甲减患者142例随机分为常规组和观察组各71例,常规组采取常规治疗方案,观察组在常规治疗基础上给予左甲状腺素片,分析两组患者的临床疗效以及对血脂、心室功能的影响。结果:连续治疗3月后,常规组、观察组的临床总有效率分别为57.7%、88.7%,组间比较,差异具有统计学意义(P<0.05);观察组治疗后血脂指标、心室功能均要优于常规组,差异具有统计学意义(P<0.05)。结论:左甲状腺素片用于治疗亚临床甲减,可以改善患者的血脂、心室功能,临床效果显著。
OBJECTIVE: To analyze the clinical efficacy of levothyroxine in the treatment of subclinical hypothyroidism and its effect on serum lipid and ventricular function. Methods: A total of 142 patients with subclinical hypothyroidism who were clinically diagnosed from April 2015 to March 2016 in Huazhou Municipal People’s Hospital were randomly divided into routine treatment group and observation group (n = 71). Conventional treatment group and observation group Levothyroxine tablets were given on the basis of routine treatment, and the clinical efficacy, blood lipid and ventricular function of the two groups were analyzed. Results: After 3 months of continuous treatment, the total clinical effective rates of routine group and observation group were 57.7% and 88.7%, respectively. The differences between the two groups were statistically significant (P <0.05). After treatment, the serum lipid, ventricular function Were better than the conventional group, the difference was statistically significant (P <0.05). Conclusion: The use of levothyroxine in the treatment of subclinical hypothyroidism can improve the blood lipid and ventricular function in patients with significant clinical effects.