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目的:研究奥美拉唑对预防重型颅脑损伤并发应激性溃疡出血的治疗效果。方法:查询我院最近3年内所接收诊治的重型颅脑损伤患者的救治资料,随机进行分组,预防性使用奥美拉唑的为治疗组,不使用的为对照组,间隔一定的时间进行疗效对比分析。结果:治疗组应激性溃疡出血的发生概率及持续时间明显的小于对照组(P<0.05),对照组采用输血治疗及大量输血治疗的比例远大于治疗组(P<0.05)。结论:奥美拉唑对于重型颅脑损伤患者并发应激性溃疡的早期预防及治疗作用显著。可以减少应激性溃疡发生的概率,降低患者并发应激性溃疡出血的出血量。
Objective: To study the therapeutic effect of omeprazole in preventing severe craniocerebral injury complicated with stress ulcer hemorrhage. Methods: Inquiring about the treatment of severe craniocerebral injury who received diagnosis and treatment in our hospital in recent 3 years, randomly divided into groups, prophylactic use of omeprazole for the treatment group, not for the control group, at a time interval for curative effect Comparative analysis. Results: The incidence and duration of stress ulcer bleeding in treatment group were significantly less than those in control group (P <0.05). The proportion of blood transfusion and blood transfusion in control group was much larger than that in treatment group (P <0.05). Conclusion: Omeprazole has a significant effect on the prevention and treatment of stress ulcer complicated by severe craniocerebral injury. Can reduce the incidence of stress ulcer, reduce the amount of bleeding in patients with stress ulcer bleeding.