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在临床上治疗病毒性疾病有效的合成药物,目前为数甚少,而且这类药物,如碘苷、阿糖胞苷、环胞苷、金刚烷胺、盐酸吗啉胍等,抗病毒谱都不广。近年来干扰素及其诱导剂类虽也应用于临床,显示出一定疗效,但其应用也受到一定限制。随着人们对病毒及其致病机理认识的发展,病毒的致病因素受到广泛重视,寻找新的广谱抗病毒药物,已成为目前努力的方向之一。
In the clinical treatment of viral diseases effective synthetic drugs, at present few, and such drugs, such as iodine glycosides, cytarabine, cytidine, amantadine, morpholine hydrochloride, etc., the anti-virus spectrum is not wide. In recent years, although interferon and its inducer are also used in clinic, it shows some curative effect, but its application is also limited. With the development of people’s understanding of the virus and its pathogenesis, the pathogenic factors of the virus have been widely regarded. Finding new broad-spectrum antiviral drugs has become one of the current efforts.