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目的 :了解青年人群血清中抗流感病毒的抗体水平和病毒变异程度。方法 :应用微量血凝素抑制试验 ,对从 1997～ 2 0 0 0年在我国 8个地区 ,每年春、秋两季 ,共采集 30 0 0份血清标本进行抗流感病毒抗体水平的检测。结果 :发现人群中抗流感病毒抗体的水平 ,在春、秋两季间波动 ;抗甲 3型流感病毒(H3N2 )的抗体水平 ,从 1999～ 2 0 0 0年保持了高水平 ;而抗甲 1型流感病毒 (H1N1)的抗体水平 ,从 1998年以来呈梯形下降 ,易感人群由 15 %上升到 75 %。结论 :近 3年中流感病毒甲 3型、甲 1型和乙型均曾在我国局部流行 ,甲 1型流感病毒 (H1N1)发生了明显变异 ,甲 3型流感病毒 (H3N2 )将可能发生变异
OBJECTIVE: To understand the anti-influenza virus antibody levels and the degree of virus variation in young people’s serum. Methods: The micro-hemagglutinin inhibition test was used to detect the anti-influenza virus antibody levels in 30 0 0 serum samples collected in 8 regions of China, spring and autumn each year from 1997 to 2000. Results: The level of anti-influenza virus antibodies in the population fluctuated between spring and autumn. The antibody level of H3N2 was maintained at a high level from 1999 to 2000. The level of antibody to type 1 influenza virus (H1N1) has been trapezoidal since 1998 and the susceptible population has risen from 15% to 75%. CONCLUSION: Influenza virus type 3, type A and type B have been endemic in China in recent 3 years. Influenza virus type 1 (H1N1) is obviously mutated and H3N2 virus may be mutated