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已普遍公认成人及动物肾上腺考的松分泌呈季节性和生理节律性波动。虽有报道男性尿17酮固醇 ((?)ks)排泄呈季节性改变,但很少有材料提示肾上腺雄激素及其代谢物的分泌和排泄呈季节性变化。本文分别在春季(5月)和秋冬季(9～12月)对22例健康绝经后妇女测定了血浆硫酸脱氢表雄酮(DHAS)水平和雄酮葡萄糖醛酸酯(AG)、本胆烷醇酮葡萄糖醛酸酯(EG)-17酮固醇的主要组成部分、5α-雄甾烷3α,17β二醇葡萄糖醛酸酯(5α-3α-Adiol G)-睾丸酮的主要代谢产物及5β-雄甾烷3α,17β二醇葡萄糖醛酸酯(5β-3α-Adiol G)-DHAS的主要代谢产物尿的排泄值,对其季节
It has been generally accepted that adult and animal adrenal cortisone secretion is seasonal and circadian rhythms. Although it has been reported that the urinary excretion of urinary 17 ketones (? Ks) seasonal changes, but few materials suggest that adrenal androgen secretion and excretion of metabolites showed a seasonal change. In this paper, we measured plasma levels of DHAS and androstenedione glucuronide (AG) in 22 healthy post-menopausal women in spring (May) and autumn and winter (September-December) Alcohol keto glucuronide (EG) -17 ketosterol, 5α-androstane 3α, 17β diol glucuronide (5α-3α-Adiol G) - the main metabolite of testosterone and 5β- Urinary excretion of the major metabolite of androstane 3α, 17β diol glucuronide (5β-3α-Adiol G) -DHAS,