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恶性肿瘤晚期常并发骨转移,尤以乳癌、肺癌、前列腺癌和鼻咽癌等多见,其特点与晚期肿瘤的脑肝转移不同,如治疗得当部分骨转移癌患者虽不能治愈却能带瘤长期生存。文献报道,大约50％的癌症患者死后尸解发现有骨转移。其中近半数临床上出现症状[1],其主要症状为难以拄制的进行性骨痛。由于其严重影响患者活动、精神、食欲、睡眠,因而解除疼痛对于提高肿瘤患者的生存质量有着至关重要的意义。本文观察自1999年1月～2002年2月用帕米磷酸二钠（博宁）治疗28例骨转移癌,止痛的总有效率（CR+PR）85.7％。取得良好的
Malignant tumors often have late bone metastases, especially breast cancer, lung cancer, prostate cancer, and nasopharyngeal cancer. Their characteristics are different from those of advanced tumors. If some patients with bone metastases are treated properly, they can be cured but can bring tumors. Long-term survival. Reported in the literature, about 50% of cancer patients found bone metastases after autopsy. Nearly half of these patients have clinical symptoms [1]. Their main symptoms are progressive bone pain that is difficult to control. Because it seriously affects the patient’s activities, spirit, appetite, and sleep, the relief of pain is of crucial importance to improve the quality of life of cancer patients. This article observed that from January 1999 to February 2002 with pamidronate disodium (BN) treatment of 28 cases of bone metastases, the total effective rate of analgesia (CR + PR) 85.7%. Get good