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急性暴发型肝衰竭(AFH)病死率较高,估计为75%,但如能抢救,有希望完全恢复.近来,有报告认为胰岛素/胰高糖素和氨基酸输注对急性重症肝炎有效,但这些制剂是否对急性肝衰竭同样有效,尚须进一步证实.皮质激素对急性重症肝炎和AFH两者的作用仍然不十分明确,有些研究表明效果肯定,有些认为无效,更有人认为非但无效,而且有害.1978年Blitzer等提出氨基半乳糖引起的家兔肝脏
Acute case of fulminant hepatic failure (AFH) has a high case fatality rate of 75%, but hopefully, if it can be salvaged, there is hope of complete recovery.Recently, insulin / glucagon and amino acid infusion are reported to be effective in acute severe hepatitis Whether these agents are as effective as acute liver failure is yet to be confirmed, and the role of corticosteroids in acute severe hepatitis and AFH remains poorly defined, with some studies showing positive results, others considered ineffective, and others considered not only ineffective but also harmful In 1978, Blitzer et al. Proposed a rabbit liver induced by galactosamine