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目的探索HIV抗体不确定样品的确证策略。方法对93例HIV抗体不确定样品的抗体检测数据进行分析,并进行病毒载量检测和HIV抗体随访检测。结果复检时两种试剂检测结果不一致的有51例,病毒载量检测结果均为阴性。两种复检试剂检测结果均为阳性的42例样品中,有27例病毒载量检测结果为阳性,其中ELISA S/CO>6的9例样品病毒载量检测结果均为阳性,ELISA S/CO≤6的33例样品中有18例病毒载量检测结果为阳性。对17例不确定样品进行了HIV抗体随访检测,11例病毒载量为阳性的样品均确证为HIV抗体阳性,6例病毒载量为阴性的样品均排除HIV感染。结论对于HIV抗体不确定样品应当慎重对待,HIV抗体复检结果和病毒载量检测结果有助于鉴别HIV感染状态。
Objective To explore the confirmation strategy of HIV antibody uncertain samples. Methods The antibody detection data of 93 HIV antibody uncertain samples were analyzed and the detection of viral load and HIV antibody follow-up were carried out. The results of the two reagents when the retest results inconsistent in 51 cases, the virus load test results were negative. Of the 42 samples positive for both retesting agents, 27 were positive for viral load, of which 9 for ELISA S / CO> 6 were all positive for viral load and for ELISA S / Of the 33 samples with CO≤6, 18 had positive viral load tests. HIV antibody follow-up tests were carried out on 17 cases of indeterminate samples. All 11 samples with positive viral load were confirmed as positive by HIV antibody. All 6 samples with negative viral load were excluded from HIV infection. Conclusions Uncertain samples of HIV antibody should be treated with caution. HIV antibody retest results and viral load test results can help identify the status of HIV infection.