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目的研究在急性肺栓塞心肺复苏中进行溶栓治疗的可行性。方法回顾分析2005年9月至2010年9月因心脏骤停行心肺复苏治疗的23例急性肺栓塞患者,其中12例给予了溶栓治疗,11例未溶栓。比较两组患者在心肺复苏后自主循环恢复及存活情况。结果溶栓治疗组自主循环恢复8例,存活5例,最终死亡7例;非溶栓治疗组自主循环恢复2例,存活1例,最终死亡10例。溶栓治疗组自主循环恢复及存活率均高于未溶栓组(P<0.05)。结论对发生心脏骤停的急性肺栓塞患者心肺复苏同时行溶栓治疗可明显提高此类患者自主循环恢复及存活率,具有较好的疗效。
Objective To study the feasibility of thrombolytic therapy in acute pulmonary embolism with cardiopulmonary resuscitation. Methods A retrospective analysis was performed on 23 patients with acute pulmonary embolism who underwent cardiopulmonary resuscitation from September 2005 to September 2010, of whom 12 received thrombolysis and 11 received no thrombolysis. The recovery and survival of spontaneous circulation after cardiopulmonary resuscitation were compared between the two groups. Results In the thrombolysis group, 8 cases recovered spontaneously, 5 survived and 7 died eventually. In the non-thrombolytic group, 2 cases recovered spontaneously, survived in 1 case and eventually died in 10 cases. Thrombolytic therapy group of spontaneous circulation recovery and survival rate were higher than the group without thrombolysis (P <0.05). Conclusions Simultaneous thrombolytic therapy of cardiopulmonary resuscitation in acute pulmonary embolism patients with cardiac arrest can significantly improve spontaneous circulation recovery and survival rate of patients with acute pulmonary embolism, and has good curative effect.