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Anti-Fas or Fas ligand can induce apoptosis whenthey bind Fas antigen on cell surfaces, and have potentialtherapeutic uses. But the disadvantage is obvious asnormal cells can also be killed. In this paper, weconstructed a fusion protein between the transmembraneand cytoplasmic domains of hfas and the HBD (hormonebinding domain) of hER (referred to as MfasER).Glioma cells transfeced with MfasER could be indued to
Anti-Fas or Fas ligand can induce apoptosis whenthey bind Fas antigen on cell surfaces, and have potential therapeutic uses. But this disadvantage is obvious as normal cells can also be killed. In this paper, weconstructed a fusion protein between the transmembrane and cytoplasmic domains of hfas and the HBD (hormonebinding domain) of hER (referred to as MfasER) .Glioma cells transfeced with MfasER could be indued to