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利用自行开发的金属植入体磁感应加热装置，对接种于裸小鼠皮下的恶性脑胶质瘤进行加热研究。该加热装置由三部分组成：①高频电流发生器；②电磁感应线圈；③金属磁性针（植入体）。在加热时，通过调整加热装置中三个部分各自相应的参数，使植入组织内的金属磁性针产生足够的治疗温度（４９℃，４７℃），加热时测定金属磁性针周围组织的温度分布发现：在正常组织中金属磁性针周围温度的下降幅度明显高于肿瘤组织，由于不同的血液动力学条件，金属磁性针在肿瘤组织中产生的热量，远大于正常组织。加热后病理学检查发现：肿瘤组织加热后在金属磁性针周围出现广泛坏死、变性，在亚急性期提示有免疫细胞参与病理过程，加热后观察肿瘤大小的变化发现：加热１周后，肿瘤随时间的推移明显缩小，而对照组肿瘤继续生长增大。
Using self-developed metal implant magnetic induction heating device, the malignant glioma inoculated on the skin of nude mice was heated. The heating device consists of three parts: ① high-frequency current generator; ② electromagnetic induction coil; ③ metal magnetic needle (implant). During heating, the metal magnetic needles in the implanted tissue generate enough treatment temperature (49 ℃, 47 ℃) by adjusting the corresponding parameters of the three parts in the heating device. The temperature distribution around the metal magnetic needles It was found that the temperature drop around the metal magnetic needle in normal tissue was significantly lower than that in the tumor tissue. Due to the different hemodynamic conditions, the heat generated by the metal magnetic needle in the tumor tissue was much larger than the normal tissue. After heating, pathological examination revealed that extensive necrosis and degeneration occurred around the metal magnetic needle after heating the tumor tissue, suggesting that immune cells involved in the pathological process during the subacute phase. After heating, the change of the tumor size was observed. After heating for 1 week, The passage of time significantly reduced, while the control group tumors continue to grow.