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血栓性血小板减少症(thrombotic thrombocy-topenic purpura,TTP)的基本病理特征为微血管血栓与血小板减少。近年来,TTP的病因与发病机制已逐步阐明,治疗效果有了根本的改观。TTP基础与临床研究的突破性成就代表了当前血液学的重大进展之一。1 ADAMTS-13在TTP发病中的意义人们对TTP的病因与发病机制进行了长期探
Thrombotic thrombocytopenia (thrombotic thrombocy-topenic purpura, TTP) of the basic pathological features of microvascular thrombosis and thrombocytopenia. In recent years, the etiology and pathogenesis of TTP has been gradually clarified, the treatment effect has been fundamentally changed. Breakthroughs in TTP basic and clinical research represent one of the major advances in current hematology. 1 ADAMTS-13 significance in the pathogenesis of TTP TTP etiology and pathogenesis of a long-term exploration