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目的调查2008-2013年成都市锦江区唐氏综合征妊娠流行病学情况。方法采用回顾性队列分析。结果 1.2008-2013年成都市锦江区唐氏综合征发生率为3.0/万。2.唐氏综合征妊娠发生率曲线随孕妇年龄增加呈现出U型或J型趋势。即位于两端的小于22周岁及大于30周岁孕妇唐氏综合征妊娠发生率较高,位于中间的22-29周岁孕妇唐氏综合征妊娠发生率较低。结论 1.2008-2013年成都市锦江区唐氏综合征妊娠发生率为3.0/万。2.唐氏综合征妊娠发生率曲线随孕妇年龄增加呈现出U型或J型趋势。即位于两端的小于22周岁及大于30周岁孕妇唐氏综合征妊娠发生率较高(发生率分别为5.5/10000及10.3/10000),位于中间的22-29周岁孕妇唐氏综合征妊娠发生率较低(发生率为0.6/10000)。
Objective To investigate the epidemiology of pregnancy in Down syndrome in Jinjiang District of Chengdu from 2008 to 2013. Methods Retrospective cohort analysis was used. Results 1. From 2008 to 2013, the incidence of Down Syndrome in Jinjiang District of Chengdu was 3.0 / million. 2. Down’s syndrome pregnancy rate curve with the increase of pregnant women showing a U-type or J-type trend. That is located in both ends of less than 22 years old and older than 30 years pregnant women with Down’s syndrome pregnancy rate is higher, located in the middle of 22-29 pregnant women with Down syndrome incidence of pregnancy is low. Conclusions 1. From 2008 to 2013, the incidence of Down’s syndrome in Jinjiang District in Chengdu was 3.0 / 10,000. 2. Down’s syndrome pregnancy rate curve with the increase of pregnant women showing a U-type or J-type trend. The incidence of Down Syndrome pregnancies in pregnant women <22 years old and> 30 years old at both ends was higher (incidence rates were 5.5 / 10000 and 10.3 / 10000, respectively), and the incidence of Down’s syndrome among pregnant women 22 to 29 years of age Lower (incidence 0.6 / 10000).