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The self-diffusion problem of Brownian particles under the constraint of quasi-one-dimensional (q1D) channel has raised wide conce. The hydrodynamic interaction (HI) plays an important role in many practical problems and two-body interactions remain dominant under q1D constraint. We measure the diffusion coefficient of individual ellipsoid when two ellipsoidal particles are close to each other by video-microscopy measurement. Meanwhile, we obtain the numerical simulation results of diffusion coefficient using finite element software. We find that the self-diffusion coefficient of the ellipsoid decreases exponentially with the decrease of their mutual distance X when X
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