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目的 :比较头孢三嗪、头孢布烯序贯疗法与单用头孢三嗪静脉输注治疗中重度下呼吸道感染的临床疗效和总医疗费用 ,选择成本低而疗效好的方案为优选方案 ,为临床合理使用抗生素 ,降低医院药品费用提供依据。方法 :3 4例中重度下呼吸道感染患者随机分为两组 ,序贯组 (A组 )采用头孢布烯序贯疗法 ,对照组 (B组 )采用头孢三嗪静脉输注疗法 ,进行成本效果分析。结果与结论 :两组具有相似的临床疗效 (P >0 .0 5 ) ,但序贯疗法与单纯静脉输注治疗相比 ,显著降低了医疗费用 (P <0 .0 5 ) ,具有药物经济学意义
OBJECTIVE: To compare the efficacy of ceftriaxone, ceftibuten and ceftriaxone alone in the treatment of moderate-to-severe lower respiratory tract infections and the total cost of treatment, and to select the optimal solution with low cost and good curative effect as the best choice for clinical Reasonable use of antibiotics to reduce hospital drug costs provide the basis. Methods: Thirty-four patients with moderate-to-severe lower respiratory tract infection were randomly divided into two groups. Sequential group (group A) received ceftibuke sequential therapy, and control group (group B) received ceftriaxone intravenous infusion. analysis. RESULTS AND CONCLUSION: The two groups had similar clinical efficacy (P> 0.05), but sequential therapy significantly reduced the medical cost (P <0.05) compared with simple intravenous infusion therapy Significance of learning