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为了观察吸入乙酸酐后机体的病理变化,在染毒柜中让大鼠吸入乙酸酐,然后在光镜下观察其吸入性损伤。结果显示:(1)急性肺水肿;(2)小支气管、细支气管粘膜凝固性坏死,炎症细胞浸润;(3)小支气管早期痉挛,后期扩张。表明引起这些损伤是由于乙酸酐对粘膜的刺激和腐蚀作用。
In order to observe the pathological changes of the body after the inhalation of acetic anhydride, the rats were ingested with acetic anhydride in an exposure cabinet and the inhalation injury was observed under a light microscope. The results showed that: (1) acute pulmonary edema; (2) bronchial and bronchial mucosal coagulative necrosis, inflammatory cell infiltration; (3) bronchial early spasm, late expansion. Show that these injuries are caused due to acetic acid on the mucous membrane stimulation and corrosion.