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巯甲丙脯氨酸(captopril) 为血管紧张素转换酶抑制剂,已证明有明显的降压作用,近来,有对正常血压伴左室衰竭者具有治疗效果的报告。著者选择了15例充血性心力衰竭患者,均男性,年龄46～70岁,病程>2月,均至少有一次心肌梗塞。病人在观察期间均为全心衰合并肺动脉高压,X线检查示心脏扩大,二维超声心动图和/或放射性核素检查示左心室扩张,收缩功能减退。心功能:10例属Ⅲ级,5例属Ⅳ级。服药前4天停用一切血管扩张剂,可继续晚间服
Captopril, an angiotensin-converting enzyme inhibitor, has been shown to have a significant antihypertensive effect and has recently been reported to have a therapeutic effect on normotensive patients with LV failure. The authors selected 15 patients with congestive heart failure, both men, aged 46 to 70 years of age, duration> 2 months, have at least one myocardial infarction. All patients underwent heart failure and pulmonary hypertension during the observation period. X-ray examination showed cardiac enlargement. Two-dimensional echocardiography and / or radionuclide examination showed left ventricular dilatation and decreased systolic function. Cardiac function: 10 cases were grade Ⅲ, 5 cases were grade Ⅳ. Four days before taking medication to disable all vasodilators, can continue to be served at night