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目的观察地佐辛预防瑞芬太尼麻醉后早期疼痛的临床疗效.方法回顾性分析我院收治的180例手术治疗患者的临床资料,其中,观察组90例患者采用手术结束前半小时左右注射地佐辛0.10mg/kg,而对照组90例患者在手术结束前十五分钟左右注射芬太尼1.0ug/kg,观察两组患者的镇痛效果、苏醒程度以及不良反应发生情况等指标.结果两组患者中,观察组在苏醒及镇痛效果指标上,显著优于对照组,有统计学差异,P<0.05;两组患者的恶心、呕吐等不良反应的发生率相比,观察组显著低于对照组,有统计学差异,P<0.05.结论地佐辛预防瑞芬太尼麻醉后早期疼痛的疗效确切,不良反应较少,值得向临床广泛推荐.“,”Objective: To observe the clinical efficacy of dezocine for preventing early pain after remifentanil Anesthesia. Methods: 180 patients with surgical treatment were divided into two groups, including 90 patients in observation group and 90 patients in control group. Results: indicators such as the awakening and the analgesic effect in the observation group were significantly better than the control group, P <0.05; incidence of adverse reactions in observed group was significantly lower than the control group, P <0.05. Conclusion: efficacy of dezocine in preventing early pain after remifentanil anesthesia is good and it is worth widely being recommended in clinical.