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选择15～18月龄 Wistar 大鼠,置于41℃高温环境中12h。其间每隔3h 向胃内灌入10%生脉散冲剂,观察生脉散预防动物中暑的效果。结果表明生脉散可降低动物死亡率,减轻心肌磷酸肌酸及 cAMP 含量的耗竭。本文还就生脉散防暑作用的某些机理进行了讨论,认为可能与该药稳定心肌能量贮备有关。结果提示生脉散对防治老年人中暑有一定应用价值。
Wistar rats aged 15-18 months were selected and placed in a high temperature environment of 41°C for 12 hours. During this time, 10% Shengmaisan granules were poured into the stomach every 3h to observe the effect of Shengmaisan on preventing animal heatstroke. The results showed that Shengmaisan can reduce animal mortality and reduce the depletion of myocardial creatine phosphate and cAMP content. This article also discusses some mechanisms of Shengmaisan’s anti-heatstroke effect and believes it may be related to the drug’s stable myocardial energy reserve. The results suggest that Shengmaisan has certain application value in preventing and treating heat stroke in the elderly.