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目的:基于文献研究小儿反复呼吸道感染非急性期证素的分布及组合规律,对其基础证的主次症进行筛选。方法:收集近20年小儿反复呼吸道感染非急性期的相关文献并整理,运用频率描述及两分类Logistic回归分析的方法进行统计分析。结果:共纳入合格文献158篇,共计339条记录。小儿反复呼吸道感染非急性期的病位证素以肺、脾为主,病性证素以气虚、阴虚、痰及血瘀为主;其组合形式以三、四证素组合最为常见,组合类型则以肺+脾+气虚、肺+气虚、肺+气虚+血瘀及肺+脾+气虚+血瘀最为常见;其基础证主要有肺脾气虚证及肺气虚证。肺脾气虚证的主症为纳差、自汗、大便溏及久咳,次症为乏力、面色萎黄及面色少华。肺气虚证的主症为恶风、恶寒、面白,次症为语声低弱、久咳、面色少华、自汗。结论:小儿反复呼吸道感染非急性期证素分布及组合存在一定的规律,可为进一步研究提供参考。
OBJECTIVE: To study the distribution and combination of non-acute syndrome factors in children with recurrent respiratory tract infections based on the literature and to screen the primary and secondary syndromes of their basic syndromes. Methods: The related literatures of non-acute stage of recurrent respiratory tract infection in children for nearly 20 years were collected and sorted out. The frequency analysis and two-class Logistic regression analysis were used for statistical analysis. Results: A total of 158 qualified documents were included, a total of 339 records. Children with recurrent respiratory tract infection in non-acute phase of the disease to lungs and spleen-based, disease syndromes to qi, Yin deficiency, phlegm and blood stasis based; combination of the three or four syndromes combination of the most common combination The type of lung + spleen + Qi, lung + Qi, lung + Qi + blood stasis and lung + spleen + Qi + blood stasis is the most common; the basic card is spleen qi deficiency and lung Qi deficiency. Spleen qi deficiency syndrome main symptoms are anorexia, spontaneous perspiration, stool and chronic cough, subacute fatigue, pale complexion and looking shaved. The main symptom of lung qi deficiency syndrome is evil wind, aversion to cold, face white, sublingual disease is hyponatremia, long cough, looking Shaohua, spontaneous. Conclusion: There is a certain regularity in the distribution and combination of non-acute syndromes in children with recurrent respiratory tract infections, which may provide reference for further research.