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先前发现,梗塞后致死性缺血性心律失常的发生同血清地高辛浓度有关,亚急性左侧星状神经节切除后,与毛地黄相关的致死性缺血性心律失常显著减少。本文研究快速β受体阻滞剂纳多洛尔(Nadolol)对地高辛治疗浓度下心肌梗塞后动物模型的心肌电生理作用和抗心律失常作用。选雌性杂种狗(14～22kg)37条,静脉麻醉后左侧开胸,游离和阻断左前降支,分置心内、外膜电极和左回旋支腔内电极。清醒状态下作心脏电生理试验和程控刺激试验并分组。11条狗选用地高辛加纳
It has previously been found that the incidence of fatal ischemic arrhythmias following infarction is related to serum digoxin concentrations and that the incidence of foxglove-related fatal ischemic arrhythmias is significantly reduced after subacute left stellate ganglionectomy. In this paper, we investigated the effects of Nadolol, a fast-acting β blocker, on myocardial electrophysiological and antiarrhythmic effects in animal models of myocardial infarction at digoxin concentrations. A total of 37 female mongrel dogs (14 ~ 22kg) were selected. Thoracotomy was performed on the left side after intravenous anesthesia. The left anterior descending branch was blocked and dissociated, and the inner and outer membrane electrodes and the left circumflex artery were separated. Awake state of cardiac electrophysiology and programmed stimulation test and grouping. 11 dogs use digoxin Ghana