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Dear Editor,Cajal bodies (CBs) are sub-nuclear bodies first described in neurons by Ramon y Cajal in 1903 and subsequently characterized in both plant and anima
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Instituto de Ingenieria Genética y Biologia Molecular(INGEBI-CONICET),Vuelta de Obligado 2490 Piso 2
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Dear Editor,Cajal bodies (CBs) are sub-nuclear bodies first described in neurons by Ramon y Cajal in 1903 and subsequently characterized in both plant and animals (Gall,2003).They appear close to the nucleoli as discrete foci whose size and number vary during the cell cycle (Strzelecka et al.,2010).They are dynamic structures that move,fuse,and separate,depending on the transcriptional status of the cell (Cioce and Lamond,2005).CBs are involved in assembly and trafficking of small nucleolar ribonucleoproteins (snoRNPs) and in assembly and trafficking of spliceosomal small nuclear ribonudeoprotein (snRNPs) complexes that are involved in mRNA splicing (Gall,2003;Cioce and Lamond,2005).
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