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目的:研究分析社区老年原发性高血压伴糖尿病患者应用氨氯地平联合缬沙坦治疗的临床效果。方法:选取我院治疗的高血压合并糖尿病患者110例,根据随机分组法对患者进行分组,每组患者55例,对照组患者应用氨氯地平片治疗,观察组患者在对照组治疗基础上给予缬沙坦胶囊口服,两组患者均治疗3个月。两组患者治疗前后分别测量血压情况,记录两组患者血糖水平指标。结果:观察组和对照组比较观察组的总有效率为98.2%高于对照组总有效率为52.7%,组间比较差异显著(P<0.05);观察组临床观察指标下降明显高于对照组,组间比较差异具有统计学意义(P<0.05)。结论:社区高血压合并高血压患者应用缬沙坦联合氨氯地平治疗,可有效降低患者血压及血糖指标,对肾功能起到保护作用,可在临床推广。
OBJECTIVE: To study the clinical effect of amlodipine combined with valsartan in the elderly with essential hypertension in the community. Methods: A total of 110 hypertensive patients with diabetes mellitus were enrolled in our hospital. Patients were divided into two groups according to the randomization method: 55 patients in each group and amlodipine tablets in control group. Patients in observation group were given treatment on the basis of control group Valsartan capsules orally, two groups of patients were treated for 3 months. Two groups of patients before and after treatment were measured blood pressure, blood glucose levels were recorded in two groups of indicators. Results: The total effective rate of the observation group and the control group was 98.2% higher than that of the control group, the total effective rate was 52.7%, the difference between the two groups was significant (P <0.05); the clinical observation index in the observation group was significantly lower than that in the control group , The difference between the groups was statistically significant (P <0.05). Conclusion: The combination of valsartan and amlodipine in patients with hypertension and hypertension in community can effectively reduce the blood pressure and blood glucose in patients, and play a protective role in renal function, and can be used clinically.