【摘 要】
：
Dear Editor,rnThe packaging of viral genomic RNA into virus particles is a critical step for virus maturation.This step includes the recognition and interaction
【机 构】
：
Wuhan Institute of Virology, Chinese Academy of Sciences,Wuhan 430071, China
论文部分内容阅读
Dear Editor,rnThe packaging of viral genomic RNA into virus particles is a critical step for virus maturation.This step includes the recognition and interaction between the nucleocapsid protein and viral RNA.The necessity of viral RNA packaging signals has been described for many RNA viruses (Cologna R,et al.,2000;Narayanan K,et al.,2001;Tchatalbachev S,et al.,2001).Occasional packaging of nongenomic viral RNAs and cellular RNAs results in noninfectious virions,and casual packaging of cellular RNA into viral particles would overwhelm the ability of viral genomic RNA to contact limited assembly factors.Therefore,viruses have probably developed a defensive strategy for the specific packaging of genomic RNA into virus particles.The packaging signals of some RNA viruses are located within more than one viral genomic region (Luytjes W,et al.,1989;Pattnaik A K,et al.,1995;Wei N,et al.,1990).For many viruses,it is unknown whether a single region or a combination of multiple genomic regions is necessary for viral RNA packaging.
其他文献
Objective:To validate the necessity of increasing the examined lymph node (ELN) count for enhancing the accuracy of prognostic evaluation of gastric cancer (GC)
Rosai-Dorfman病,又称窦组织细胞增生伴巨大淋巴结病,是一种罕见的组织细胞病,通常表现为青少年的无痛性双侧颈部淋巴结肿大.Rosai-Dorfman病发病累及骨骼者不到10％,并且多达7
Objective:Ultrasonically activated shears (UAS) have been applied in open gastric surgeries with no or little evidence.It was previously reported about the surg
Dear Editor,rnNucleotide and protein sequences of isolates collected from infected populations can be useful for determining the threats,such as host adaptation
2000年版(下简称现版药典)正式执行已两年余,本版药典吸收了国内外新的科研成果和现代分析技术,与1995年版比较整体水平有了明显的改进和提高.
Dear Editor,rnSevere Acute Respiratory Syndrome (SARS) has been described as the first pandemic of the 21 st century and between November 2002 and July 2003,ove
Dear Editor,rnTo establish a more specific diagnostic assay than the current methods for rabies virus (RABV) infection in canines and wildlife species,we develo
Objective:To compare the effect of neoadjuvant chemotherapy (NACT) with adjuvant chemotherapy (ACT) using oxaliplatin plus S-1 (SOX) or capecitabine (CapeOX) on
目的找出护理质量评价的关键指标，构建统一的上海市三级综合医院护理质量评价关键指标体系。方法通过查阅文献资料、进行专家访谈，以Donabedian的"三维质量结构"为理论框架，识别影响护理质量的因素，采用德尔菲法咨询护理专家14名，对评价指标进行论证，初步确立上海市三级综合医院护理质量评价关键指标体系。结果经过2轮专家咨询确立了3项一级指标、12项二级指标、48项三级指标及相应的权重值。结论通过初步