Influence of HLA gene polymorphisms on susceptibility and outcome post infection with the SARS-CoV v

• 作 者: Fang Fang Yuan Zlatibor Velickovic Lesley J Ashton Wayne B Dyer Andrew F Geczy Heather Dunckley Garry W Lynch
• 机 构: Central Clinical School, Sydney Medical School, University of Sydney, NSW 2006, Australia“,”Departme
• 出 处: 中国病毒学
• 发表日期: 2014年2期
• 关键词: human leukocyte antigen

Dear Editor,rnSevere Acute Respiratory Syndrome (SARS) has been described as the first pandemic of the 21 st century and between November 2002 and July 2003,over 8000 people were infected with the SARS-associated coronavirus (SARS-CoV).Polymorphisms in the human leukocyte antigen (HLA) system have been shown to influence susceptibility to SARS-CoV but here we were unable to demonstrate any association between HLA and susceptibility or outcome post infection with the SARS-CoV.