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目的:评价甲硝唑与克林霉素联用治疗细菌性阴道炎患者抗感染的临床疗效。方法:选取2013年6月—2015年1月间收治的细菌性阴道炎患者200例,将其分甲硝唑组和联用组,每组100例;甲硝唑组患者给予甲硝唑抗感染治疗,联合组患者给予甲硝唑与克林霉素联用抗感染治疗,评价两组患者近期疗效、远期疗效和治疗后的生活质量评分值。结果:联合组患者近期疗效明显高于甲硝唑组(P<0.05),远期复发率明显低于甲硝唑组(P<0.05),生活质量的评分值优于甲硝唑组(P<0.05)。结论:甲硝唑与克林霉素联用治疗细菌性阴道炎患者的临床疗效优于单用甲硝唑的疗效,且疗效确切,近远期疗效较好,有利于改善患者临床症状和生活质量。
Objective: To evaluate the clinical efficacy of metronidazole in combination with clindamycin in the treatment of bacterial vaginosis. Methods: 200 cases of bacterial vaginosis admitted between June 2013 and January 2015 were selected and divided into metronidazole group and combination group, with 100 cases in each group. Patients in metronidazole group were given metronidazole Infections treatment, combined group of patients given metronidazole and clindamycin in combination with anti-infection treatment, evaluation of two groups of patients with short-term efficacy, long-term efficacy and quality of life after treatment scores. Results: The curative effect in the combined group was significantly higher than that in the metronidazole group (P <0.05), and the long-term recurrence rate was significantly lower in the metronidazole group (P <0.05). The quality of life score was better than the metronidazole group <0.05). Conclusion: The clinical effect of metronidazole combined with clindamycin in the treatment of bacterial vaginosis is superior to that of metronidazole alone. The curative effect is definite, and the curative effect in short and long term is good, which is beneficial to improve the clinical symptoms and life of patients quality.