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目的:评价甲氨蝶呤与米非司酮联用对孕妇异位妊娠的临床疗效。方法:选取2014年5月—2015年5月间诊治的异位妊娠孕妇100例,将其随机分为治疗组和对照组,每组50例;对照组患者均给予单用米非司酮治疗,治疗组在对照组治疗的基础上加用甲氨蝶呤治疗,比较两组患者治疗后的总有效率和不良反应的发生率。结果:经治疗,治疗组患者治疗的总有效率为92.00%明显高于对照组为76.00%(P<0.05);治疗过程中两组患者均未发生严重不良反应症状。结论:甲氨蝶呤与米非司酮联用对孕妇异位妊娠的疗效优于单用米非司酮的临床疗效,且患者用药期间未发生严重不良反应症状。
Objective: To evaluate the clinical efficacy of methotrexate combined with mifepristone on pregnant women with ectopic pregnancy. Methods: 100 cases of ectopic pregnancy diagnosed and treated between May 2014 and May 2015 were selected and randomly divided into treatment group and control group, 50 cases in each group. Patients in control group were given mifepristone alone , The treatment group was treated with methotrexate on the basis of the control group, and the total effective rate and the incidence of adverse reactions after treatment were compared between the two groups. Results: After treatment, the total effective rate of the treatment group was 92.00%, which was significantly higher than that of the control group (76.00%, P <0.05). No serious adverse reactions occurred in both groups during the treatment. Conclusion: The combination of methotrexate and mifepristone has better curative effect on ectopic pregnancy than that of mifepristone alone, and no serious side effects occurred during the course of medication.