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肾上腺皮质激素(简称激素)治疗肾病综合征过去10多年中应用日益广泛。但有一些病人由于滥用或应用不当,反使病情加重,带来了严重的后果。今结合具体病例,谈谈使用激素的体会。一、应用激素要注意适应证的选择肾病综合征是由多种病因引起的一组临床综合征。治疗反应和预后差别很大。激素对微小病变型肾病有效率可达93%,其中成人占20%左右,激素只对这20%的肾病综合征肯定有效。从临床类型选择:激素对大部分原发性肾病综合征Ⅰ型疗效较好;Ⅱ型部分有效或完全无效;在继发性肾病综合征中,除狼疮性肾炎外,大多疗效较差。例1:患者男,52岁。腰痛、尿少、反复浮
Adrenal cortex hormone (referred to as hormone) treatment of nephrotic syndrome in the past 10 years, more and more widely used. However, some patients have serious consequences due to misuse or misapplication, thereby aggravating the condition. Now combined with specific cases, talk about the use of hormones. First, the application of hormones should pay attention to the choice of indications Nephrotic syndrome is caused by a variety of causes of a group of clinical syndromes. Treatment response and prognosis vary greatly. Hormone on minimally pathological nephropathy up to 93% efficiency, of which adults accounted for about 20%, hormone only 20% of these nephrotic syndrome certainly effective. Select from the clinical type: hormone for most of the primary nephrotic syndrome type Ⅰ better effect; Ⅱ part of the effective or completely ineffective; secondary nephrotic syndrome, except for lupus nephritis, most of the less effective. Example 1: Male patient, 52 years old. Low back pain, oliguria, repeated floating