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目的 了解环丙沙星治疗小儿急性菌痢疗效及副作用.方法 同期住院病例随机分为环丙沙星治疗组及毗哌酸治疗对照组,疗程5天,然后将两组治疗愈率及临床主要观察指标进行统计学处理.结果 治疗组显效率为84.7%,对照组为26.7%,两组比较有显著差异(P<0.05).临床主要指标恢复日,治疗组明显短于对照组(P<0.05).治疗组不良反应发生率为15.2%,主要以消化道反应为主,停药后不良反应可自行消失.结论 环丙沙星治疗小儿急性菌痢疗效显著,安全可靠.
Objective To understand the curative effect and side effects of ciprofloxacin in the treatment of acute bacillary dysentery in children.Methods The hospitalized patients in the same period were randomly divided into ciprofloxacin group and adjuvant acid treatment group.The course of treatment was 5 days.Then the two groups were treated and clinical main Results The effective rate of treatment group was 84.7% and that of control group was 26.7%, there was significant difference between the two groups (P <0.05) .The clinical main index recovery day, the treatment group was significantly shorter than the control group (P < 0.05) .The incidence of adverse reactions in the treatment group was 15.2%, mainly in the gastrointestinal tract, and the adverse reactions could disappear on their own after the treatment was stopped.Conclusion Ciprofloxacin is effective and safe in treating children with acute bacillary dysentery.