Bacteriostatic Study on Cortex Moutan and Radix Paeoniae Rubra Extract

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[Objective] The aim was to discuss the inhibition of Cortex Moutan and Radix Paeoniae Rubra extract to bacteria and then provide further information to develop the two new medicine. [Method] Variant concentration of Cortex Moutan and Radix Paeoniae Rubra extract was studied to the inhibition of six food-borne microorganisms and pathogens and determination of the minimum inhibitory concentration (MIC) by employing filter paper diffusion method. [Result] The Cortex Moutan extract has stronger bacteriostasis activity to the S.typhimurium and E.coli with 0.09 and 0.11 mg/ml as their MIC, respectively, while relatively lower inhibition to S.aureus and S.faecalis; however, Radix Paeoniae Rubra extract has stronger bacteriostasis activity to the L.monocytogenes and S.typhimurium with 0.10 and 0.19 mg/ml as their MIC, respectively, but little inhibition to S.faecalis. [Conclusion] Both of the Cortex Moutan and Radix Paeoniae Rubra extract have some bacteriostasis activity to the six food-borne microorganisms and pathogens. [Objective] The aim was to discuss the inhibition of Cortex Moutan and Radix Paeoniae Rubra extract to bacteria and then provide further information to develop the two new medicine. [Method] Variant concentration of Cortex Moutan and Radix Paeoniae Rubra extract was studied to the inhibition of Six food-borne microorganisms and pathogens and determination of the minimum inhibitory concentration (MIC) by employing filter paper diffusion method. [Result] The Cortex Moutan extract has stronger bacteriostasis activity to the S. typhimurium and E. coli with 0.09 and 0.11 mg / ml as their MIC, respectively, while relatively lower inhibition to S.aureus and S. faecalis; however, Radix Paeoniae Rubra extract has stronger bacteriostasis activity to the L. monocytogenes and S. typhimurium with 0.10 and 0.19 mg / ml as their MIC , respectively, but little inhibition to S. faecalis. [Conclusion] Both of the Cortex Moutan and Radix Paeoniae Rubra extract have some bacteriostasis activity to the six food-borne microorganisms and pathogens.
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