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目的观察辛伐他汀治疗急性脑梗死的血脂变化情况及临床疗效。方法将72例急性脑梗死患者随机分为对照组37例,治疗组35例,观察30天后两组患者的血脂参数及临床疗效。结果治疗组Tc、Tg、HDL-c、LDL-c治疗后均有明显降低(P<0.05),治疗组与对照组治疗后比较差异有显著意义(P<0.05),治疗组神经功能缺损评分、临床疗效均优于对照组,两组间比较差异有显著意义(P<0.05)。结论:辛伐他汀治疗急性脑梗死有效。
Objective To observe the changes of blood lipids and clinical effects of simvastatin in patients with acute cerebral infarction. Methods Seventy-two patients with acute cerebral infarction were randomly divided into control group (n = 37) and treatment group (n = 35). The blood lipid parameters and clinical efficacy of the two groups were observed after 30 days. Results The levels of Tc, Tg, HDL-c and LDL-c in the treatment group were significantly decreased (P <0.05), and there was significant difference between the treatment group and the control group after treatment (P0.05). The neurological deficit score , The clinical curative effect was better than the control group, the difference between the two groups was significant (P <0.05). Conclusion: Simvastatin is effective in treating acute cerebral infarction.